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Free U.S. shipping over $30  ·  HSA/FSA accepted  ·  Rx reviewed by licensed physicians  ·  Cancel anytime
Valura Health
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RX Skin Tretinoin Cream 0.025% cream
Prescription — physician review required FDA-approved HSA/FSA eligible

Tretinoin Cream

Tretinoin is the original prescription retinoid, with five decades of evidence for acne and photoaged skin. Stronger than any over-the-counter retinol.

  • The gold-standard prescription retinoid
  • Evidence for acne, texture, tone, and fine lines
  • Titrated strength chosen by your clinician
  • Our Night Shift retinol's stronger sibling
Strength (final choice is your clinician's)
Purchase option
Monthly plan Refills ship monthly after approval · pause or cancel anytime $35/mofree shipping
  • Checkout includes a short health questionnaire — reviewed by a licensed physician, usually within 24h
  • Full refund if treatment isn't approved · Illinois only at launch
Filled & shipped by Valura Demo Pharmacy An independent, US-licensed pharmacy. Your prescription transmits electronically after physician approval — nothing ships without a clinician's sign-off.
How getting this works+

Complete a short online health questionnaire at checkout. A licensed physician at Valura Medical, S.C. reviews your answers — usually within 24 hours — and, if appropriate, issues a prescription that is sent electronically to our partner pharmacy, which ships it to your door. If treatment isn't right for you, you'll get a full refund and a note explaining why.

No subscription starts until a clinician approves your treatment.

Retinol vs. tretinoin+

Retinol (our OTC Night Shift cream) must convert in the skin before it works; tretinoin arrives already active — more powerful, and more demanding. If you're retinoid-new, many start OTC and upgrade.

Important safety information+

Not for use during pregnancy or while trying to become pregnant. Expect dryness and irritation in early weeks; use sunscreen daily — tretinoin increases sun sensitivity. Your clinician will guide titration.

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