RX
Longevity
Low-Dose Naltrexone (LDN)
1.5 mg (titration start)
Low-Dose Naltrexone (LDN)
The quiet favorite for inflammation balance and wellbeing — compounded per patient.
From $39/mo
Rx
Metformin has been prescribed for 65+ years, and it's the molecule behind the landmark TAME longevity trial. Prescribed off-label for metabolic health and healthy aging in appropriate patients.
Complete a short online health questionnaire at checkout. A licensed physician at Valura Medical, S.C. reviews your answers — usually within 24 hours — and, if appropriate, issues a prescription that is sent electronically to our partner pharmacy, which ships it to your door. If treatment isn't right for you, you'll get a full refund and a note explaining why.
No subscription starts until a clinician approves your treatment.
Longevity benefit in healthy adults is a hypothesis under active study — that's exactly what the TAME trial exists to test. What's established: decades of metabolic benefit data. Your clinician will discuss whether the evidence fits your situation, and may recommend baseline kidney labs first.
Metformin is prescribed off-label for longevity/metabolic health. It is not appropriate with significant kidney disease, liver disease, or heavy alcohol use (lactic acidosis risk, rare but serious). GI side effects are common early and usually settle; long-term use can lower B12 — periodic checks are wise. Hold before surgery or contrast imaging. Your clinician will review your kidney function history and may require labs.
The quiet favorite for inflammation balance and wellbeing — compounded per patient.